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TranscriptomicsFunctional dissection of ovarian aging-associated genes NDUFS5 and UBE2L3 through integrated genomic analyses and validation
Ovarian aging, culminating in menopause, involves a gradual decline in ovarian function. Genetic factors influencing age at natural menopause (ANM) especially premature ovarian insufficiency (POI) warrant further research. We employed a Bayesian framework to integrate a genome-wide association study...
ORGANISM(S): Homo sapiens 
2026-01-23 | GSE288033 | GEO
UnknownVariants on the UBE2L3/YDJC Autoimmune Disease Risk Haplotype Increase UBE2L3 Expression by Modulating CCCTC-Binding Factor and YY1 Binding.
Not available
S-EPMC8712360 | biostudies-literature
GenomicsFunctional dissection of ovarian aging-associated genes NDUFS5 and UBE2L3 through integrated genomic analyses and validation
Functional dissection of ovarian aging-associated genes NDUFS5 and UBE2L3 through integrated genomic analyses and validation
PRJNA1215751 | ENA
UnknownUBE2L3 expression in human gastric cancer and its clinical significance.
Not available
S-EPMC11043109 | biostudies-literature
UnknownA functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus.
Not available
S-EPMC3411915 | biostudies-literature
UnknownMechanism and Disease Association With a Ubiquitin Conjugating E2 Enzyme: UBE2L3.
Not available
S-EPMC8899012 | biostudies-literature
UnknownUBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.
Not available
S-EPMC4320258 | biostudies-literature
UnknownUBE2L3, a Partner of MuRF1/TRIM63, Is Involved in the Degradation of Myofibrillar Actin and Myosin.
Not available
S-EPMC8392593 | biostudies-literature
UnknownThe haplotype of UBE2L3 gene is associated with Hashimoto's thyroiditis in a Chinese Han population.
Not available
S-EPMC4837539 | biostudies-literature
UnknownIL-1β turnover by the UBE2L3 ubiquitin conjugating enzyme and HECT E3 ligases limits inflammation.
Not available
S-EPMC10359330 | biostudies-literature
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