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TranscriptomicsTranscription profiling of human hepatocellular carninoma HepG2 cell lines exposed to single dose of Benzo[a]pyrene (BaP) in a time-course over 60 hours and 11 time points
Not available
ORGANISM(S): ATCC 
2010-07-01 | E-TOXM-23 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human hepatocellular carninoma HepG2 cell lines exposed to single dose of Benzo[a]pyrene (BaP) in a time-course over 60 hours and 11 time points
Not available
ORGANISM(S): Homo sapiens 
2010-07-01 | E-TOXM-22 | biostudies-arrayexpress
TranscriptomicsComparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver
At present, substantial efforts are focused on the development of in vitro assays coupled with M-bM-^@M-^]omicsM-bM-^@M-^] technologies for the identification of carcinogenic substances as an alternative to the classical 2-year rodent carcinogenicity bioassay. A prerequisite for the eventual regulat...
ORGANISM(S): Rattus norvegicus 
2012-04-23 | E-GEOD-36524 | biostudies-arrayexpress
TranscriptomicsTranscriptomic response to benzo[a]pyrene treatment in HepG2 cells (RNA-Seq)
Whole-genome transcriptome measurements are pivotal for characterizing carcinogenic mechanisms of chemicals and predicting toxic classes, such as genotoxicity, from in vitro and in vivo assays. DNA microarrays have evolved as the gold standard for this purpose. In recent years deep sequencing techno...
ORGANISM(S): Homo sapiens 
2012-11-16 | E-GEOD-36242 | biostudies-arrayexpress
TranscriptomicsTranscriptomic response to benzo[a]pyrene treatment in HepG2 cells (Affymetrix)
Whole-genome transcriptome measurements are pivotal for characterizing carcinogenic mechanisms of chemicals and predicting toxic classes, such as genotoxicity, from in vitro and in vivo assays. DNA microarrays have evolved as the gold standard for this purpose. In recent years deep sequencing techno...
ORGANISM(S): Homo sapiens 
2012-11-16 | E-GEOD-36243 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human hepatoma cell lines HepG2 and HepaRG using whole genome gene expression analysis before and after exposure to the GTX carcinogens AFB1 and BaP, and the NGTX carcinogens CsA, E2 and TCDD for 12 and 48 h
Direct comparison of the hepatoma cell lines HepG2 and HepaRG using whole genome gene expression analysis before and after exposure to the GTX carcinogens AFB1 and BaP and the NGTX carcinogens CsA, E2 and TCDD for 12 and 48 h.
ORGANISM(S): Homo sapiens 
2010-04-15 | E-MEXP-2458 | biostudies-arrayexpress
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