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GenomicsCharacterization of SOC1’s central role in flowering by the identification of its upstream and downstream regulators
The transition from vegetative to reproductive development is one of the most important phase changes in the plant life cycle. This step is controlled by various environmental signals that are integrated at the molecular level by so-called floral integrators. One such floral integrator in Arabidopsi...
ORGANISM(S): Arabidopsis thaliana 
2013-04-09 | E-GEOD-45846 | biostudies-arrayexpress
UnknownPursuing Orally Bioavailable Hepcidin Analogues via Cyclic N-Methylated Mini-Hepcidins.
Not available
S-EPMC7915682 | biostudies-literature
GenomicsEpigenetic Profiling of Human Colorectal Cancer

DNA methylation, together with chromatin modifications, constitute the epigenome that functions to regulate gene expression and genome integrity. DNA methylation alterations are ubiquitous in human cancers, as many genes acquire DNA methylation in a cancer-specific manner. DNA methylation at thes...

phs000385.v1.p1 | EGA
TranscriptomicsProbing the effect of promoters on noise in gene expression using thousands of designed sequences
Genetically identical cells exhibit large variability (noise) in gene expression, with important consequences for cellular function. Although the amount of noise decreases with and is thus partly determined by the mean expression level, the extent to which different promoter sequences can deviate aw...
ORGANISM(S): synthetic construct 
2014-07-12 | E-GEOD-55346 | biostudies-arrayexpress
ProteomicsMice retina proteomic in the study of gaptch11 in Leber Congenial Amaurosis
Leber Congenial Amaurosis (LCA) is the most severe early-onset type of blindness that affects children. Several genes have been discovered to be involved in the disease, Gpatch11 being one of them, which needs to be studied deeply. We identified an homozygous variant in the splicing site of exon4 r...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-27 | PXD041849 | Pride
Leber congenial amaurosis Lca Gpatch11 Retina 
ProteomicsMice retina proteomic in the study of gaptch11 in Leber Congenial Amaurosis
Leber Congenial Amaurosis (LCA) is the most severe early-onset type of blindness that affects children. Several genes have been discovered to be involved in the disease, Gpatch11 being one of them, which needs to be studied deeply. We identified an homozygous variant in the splicing site of exon4 r...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-27 | PXD051363 | Pride
Leber congenial amaurosis Immunoprecipitation Gpatch11 Mouse Retina 
TranscriptomicsPFOS and PFHxS decrease lipoprotein production
The effect of perfluoroalkyl sulfonates on lipoprotein metabolism was investigated in APOE*3-Leiden.CETP mice with a humanized lipoprotein profile. Perfluorohexane sulfonate and perfluorooctane sulfonate markedly reduced both plasma TG and TC by decreasing nonHDL-C and HDL-C accompanied by a reducti...
ORGANISM(S): Mus musculus 
2011-01-01 | E-GEOD-22940 | biostudies-arrayexpress
UnknownPrediction of Outcome and Endovascular Treatment Benefit: Validation and Update of the MR PREDICTS Decision Tool.
Not available
S-EPMC8378416 | biostudies-literature
UnknownHealthy Life-Year Costs of Treatment Speed From Arrival to Endovascular Thrombectomy in Patients With Ischemic Stroke: A Meta-analysis of Individual Patient Data From 7 Randomized Clinical Trials.
Not available
S-EPMC8094030 | biostudies-literature
UnknownGenetic correlates of phenotypic heterogeneity in autism.
Not available
S-EPMC9470531 | biostudies-literature
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