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TranscriptomicsSodium arsenite induced gene expression changes in A549 human epithelial lung carcinoma cells
Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patterns which could lead to altered gene expression Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 ...
ORGANISM(S): Homo sapiens 
2014-09-17 | E-GEOD-44169 | biostudies-arrayexpress
TranscriptomicsSodium arsenite induced DNA methylation changes in A549 human epithelial lung carcinoma cells
Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patterns Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 M-BM-5M, 0.4 M-BM-5M and 2 M-BM-5M for 1, 2 ...
ORGANISM(S): Homo sapiens 
2014-09-17 | E-GEOD-44173 | biostudies-arrayexpress
TranscriptomicsSodium arsenite induced changes in A549 human epithelial lung carcinoma cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-09-17 | E-GEOD-44174 | biostudies-arrayexpress
TranscriptomicsExpression Profiles of HepG2 cells treated with 22 compounds and solvent controls
The transcriptomics changes induced in the human liver cell line HepG2 by 17 hepatotoxic compounds, 5 non-hepatotoxic compounds and solvent controls after treatment for 24h The study investigated differential gene expression in HepG2 cell line mRNA following 24 hours of exposure to 17 hepatotoxic co...
ORGANISM(S): Homo sapiens 
2014-02-14 | E-GEOD-51952 | biostudies-arrayexpress
UnknownMicro-mechanical insights into the dynamics of crack propagation in snow fracture experiments.
Not available
S-EPMC8175457 | biostudies-literature
TranscriptomicsGenotoxic Carcinogen response in primary mouse hepatocytes
Gene expression changes to several compounds in primary hepatocytes of wildtype and Xpa-/-p53+/- mice
ORGANISM(S): Mus musculus 
2018-04-06 | E-MTAB-665 | biostudies-arrayexpress
UnknownHuman milk extracellular vesicles preserve bronchial epithelial barrier integrity and reduce TLR3‐induced inflammation in vitro
Not available
S-EPMC11080843 | biostudies-literature
UnknownDog ownership satisfaction determinants in the owner-dog relationship and the dog's behaviour.
Not available
S-EPMC6147508 | biostudies-literature
TranscriptomicsExtensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells (miRNA)
Understanding toxicity pathways of engineered nanomaterials (ENM) has recently been brought forward as a key step in 21st century ENM risk assessment. Molecular mechanisms linked to phenotypic end points is a step towards the development of toxicity tests based on key events, which may allow for gro...
ORGANISM(S): Homo sapiens 
2015-04-02 | E-GEOD-63559 | biostudies-arrayexpress
TranscriptomicsDietary titanium dioxide (E171) increases systemic ROS levels and alters the colon transcriptome – Evidence from a human dietary intervention study
This study provides critical insights into the adverse effects of titanium dioxide (E171) on human gastrointestinal health and its potential molecular mechanisms of action, marking a significant advancement in food toxicology. Through a human dietary intervention study involving 31 participants cons...
ORGANISM(S): Homo sapiens 
2025-09-30 | E-MTAB-15089 | biostudies-arrayexpress
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