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UnknownThe evolution of domain-content in bacterial genomes.
Not available
S-EPMC2615428 | biostudies-literature
UnknownProbabilistic clustering of sequences: inferring new bacterial regulons by comparative genomics.
Not available
S-EPMC124229 | biostudies-literature
TranscriptomicsChromatin based modeling of transcription rates identifies the contribution of different regulatory layers to steady-state mRNA levels.
Messenger RNA levels in eukaryotes are balanced by two consecutive regulatory layers. Primary, transcriptional regulation at the level of chromatin and secondary, post-transcriptional regulation of the initial transcript in the cytoplasm. Each layer is individually studied in mechanistic detail, whi...
ORGANISM(S): Mus musculus 
2012-09-13 | E-GEOD-34473 | biostudies-arrayexpress
UnknownE. coli prepares for starvation by dramatically remodeling its proteome in the first hours after loss of nutrients
Not available
S-SCDT-10_1038-S44320-026-00226-5 | biostudies-other
TranscriptomicsChromatin based modeling of transcription rates identifies the contribution of different regulatory layers to steady-state mRNA levels
Messenger RNA levels in eukaryotes are balanced by two consecutive regulatory layers. Primary, transcriptional regulation at the level of chromatin and secondary, post-transcriptional regulation of the initial transcript in the cytoplasm. Each layer is individually studied in mechanistic detail, whi...
ORGANISM(S): Mus musculus 
2012-07-23 | E-GEOD-33252 | biostudies-arrayexpress
TranscriptomicsThe systematic shortening of 3’ UTRs has limited influence on the relative change in protein abundance in proliferating cells
Alternative polyadenylation is an important cellular mechanism that enables generation of mRNA isoforms that differ in their 3' untranslated regions (3' UTRs) and consequently in their susceptibility to miRNA and RNA binding protein mediated regulation. A dramatic change in polyadenylation site usa...
ORGANISM(S): Homo sapiens 
2014-09-25 | E-GEOD-54950 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of liver biopsies from 21 chronic hepatitis C patients undergoing antiviral therapy
This dataset is part of the paper: Pegylated interferon-α regulates hepatic gene expression by transient activation of the Jak-STAT pathway; Dill MT et al; Journal of Clinical Investigation; in review Pegylated interferon-α (pegIFN-α) has replaced un-modified recombinant IFN-α for the treatment of c...
ORGANISM(S): Homo sapiens 
2014-01-30 | E-GEOD-48445 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation to determine binding of ARS binding factor 1 (Abf1) in yeast during vegetative growth and meiotic development
Binding of the yeast ARS binding factor 1 (Abf1) to target promotors during vegetative growth and meiotic development as tested by ChIP-CHIP analysis;
ORGANISM(S): Saccharomyces cerevisiae 
2008-05-01 | E-MEXP-1439 | biostudies-arrayexpress
GenomicsA comparative epigenomics approach reveals REST as a mediator of Polycomb reprogramming during neuronal differentiation
Transcription factors (TFs) in concert with chromatin pathways stably reset transcriptional programs during differentiation. Yet we know little how local sites of chromatin reprogramming are specified and how the estimated 3000 TF encoded in mammalian genomes contribute to chromatin dynamics. To ide...
ORGANISM(S): Mus musculus 
2012-09-04 | E-GEOD-27148 | biostudies-arrayexpress
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