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We made deletions of Med2, Med3, Med18, Med20 and a C-terminal truncation of Med8. We expression profiled the mutants against a common reference.
ORGANISM(S): Saccharomyces cerevisiae 
To understand relationships between phosphorylation-based signaling pathways, we analyzed 150 deletion mutants of protein kinases and phosphatases in S. cerevisiae using DNA microarrays. Downstream changes in gene expression were treated as a phenotypic readout. Double mutants with synthetic genetic...
ORGANISM(S): Saccharomyces cerevisiae 
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