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TranscriptomicsGenetic Aberrations Relate Early and Advanced Stage Ovarian Cancer and are Associated with Survival
BACKGROUND: Because of the distinct clinical presentation of early and advanced stage ovarian cancer, we aim to clarify whether these disease entities are solely separated by time of diagnosis or whether they arise from distinct molecular events. METHODS: Sixteen early and sixteen advanced stage ova...
ORGANISM(S): Homo sapiens 
2012-08-22 | E-GEOD-24418 | biostudies-arrayexpress
TranscriptomicsSmall bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers
Purpose: Small bowel adenocarcinoma (SBA) is a rare cancer and consequently the number of clinical trials has been very limited due to the small numbers of patients. Chemotherapy regimens are currently rather arbitrarily chosen between either a colorectal (CRC) or a gastric cancer (GC) regimen. Chr...
ORGANISM(S): Homo sapiens 
2011-06-13 | E-GEOD-23418 | biostudies-arrayexpress
TranscriptomicsHNSCC Cells: ctrl vs six tumour lethal miRNAs transfected
Some microRNAs have antiproliferative effects in cells and are believed to act as tumour suppressors. We used a retroviral human microRNA expression library to identify six microRNAs, miR-181a, miR-323, miR-326, miR-342, miR345 and miR-371, that induce antiproliferative effects in head and neck squa...
ORGANISM(S): Homo sapiens 
2013-11-06 | E-GEOD-34881 | biostudies-arrayexpress
TranscriptomicsAltered microRNA expression associated with chromosomal and epigenetic changes contributes to cervical carcinogenesis
Little is known about the alterations in microRNA (miRNA) expression patterns during the consecutive stages of cervical cancer development and their association with chromosomal instability and epigenetic changes. We integrated miRNA expression profiles in normal cervical squamous epithelium, high-g...
ORGANISM(S): Homo sapiens 
2012-06-27 | E-GEOD-30656 | biostudies-arrayexpress
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