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TranscriptomicsUsing breast (cancer) cell lines to measure bortezomib therapy response
Revealing targeted therapy for human cancer by gene module maps A major goal of cancer research is to match specific therapies to molecular targets in cancer. Genome-scale expression profiling has identified new subtypes of cancer based on consistent patterns of variation in gene expression, leading...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-5307 | biostudies-arrayexpress
TranscriptomicsMicroRNA sequence and expression analysis in breast tumors by deep sequencing
This SuperSeries is composed of the following subset Series: GSE29173: MicroRNA sequence and expression analysis in breast tumors by deep sequencing [miRNA sequence data] GSE29174: MicroRNA sequence and expression analysis in breast tumors by deep sequencing [mRNA expression array data] MicroRNAs (m...
ORGANISM(S): Homo sapiens 
2011-06-07 | E-GEOD-28884 | biostudies-arrayexpress
TranscriptomicsMicroRNA sequence and expression analysis in breast tumors by deep sequencing [mRNA expression array data]
MicroRNAs (miRNAs) regulate many genes critical for tumorigenesis. We profiled miRNAs from 11 normal breast tissues, 17 non-invasive, 151 invasive breast carcinomas, and 6 cell lines by in-house-developed barcoded Solexa sequencing. miRNAs were organized in genomic clusters representing promoter-con...
ORGANISM(S): Homo sapiens 
2011-06-07 | E-GEOD-29174 | biostudies-arrayexpress
TranscriptomicsMicroRNA sequence and expression analysis in breast tumors by deep sequencing [miRNA sequence data]
MicroRNAs (miRNAs) regulate many genes critical for tumorigenesis. We profiled miRNAs from 11 normal breast tissues, 17 non-invasive, 151 invasive breast carcinomas, and 6 cell lines by in-house-developed barcoded Solexa sequencing. miRNAs were organized in genomic clusters representing promoter-con...
ORGANISM(S): Homo sapiens 
2011-06-06 | E-GEOD-29173 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human radiation associated breast cancers reveals distinct subtypes
BfHL's, spor zonder BfNHL's en BfHL4
ORGANISM(S): Homo sapiens 
2010-02-18 | E-NCMF-30 | biostudies-arrayexpress
TranscriptomicsIntegrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
Abstract BACKGROUND: The basal-like breast cancer (BLBC) subtype is characterized by positive staining for basal mammary epithelial cytokeratin markers, lack of hormone receptor and HER2 expression, and poor prognosis with currently no approved molecularly-targeted therapies. The oncogenic signaling...
ORGANISM(S): Homo sapiens 
2016-08-21 | E-GEOD-74667 | biostudies-arrayexpress
GenomicsBreast Cancer Histology Images
Fresh frozen breast cancer H&E tissue images collected and annotated by the International Cancer Genome Consortium (ICGC), that included the BASIS collaboration. Associated with whole genome sequence data as originally described by Nik-Zainal et al, Nature, 2016 (DOI: 10.1038/nature17676) and de...
EGAD00010001911 | EGA
GenomicsICGC breast cancer sequencing project SNP6 data
Affymetrix SNP6.0 breast cancer genome sequencing data
EGAD00010000915 | EGA
GenomicsEGAS00001000195-sc-20150416 - samples
We propose to definitively characterise the somatic genetics of breast cancer through generation of comprehensive catalogues of somatic mutations in breast cancer cases by high coverage genome sequencing coupled with integrated transcriptomic and methylation analyses.
EGAD00001001337 | EGA
GenomicsEGAS00001000042-sc-20150416 - samples
We propose to definitively characterise the somatic genetics of breast cancer through generation of comprehensive catalogues of somatic mutations in breast cancer cases by high coverage genome sequencing coupled with integrated transcriptomic and methylation analyses.
EGAD00001001334 | EGA
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