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ProteomicsSyntaxin-3 is a Weibel-Palade body localized SNARE protein that regulates Von Willebrand factor secretion from endothelial cells
Endothelial cells store von Willebrand factor (VWF) in rod-shaped secretory organelles, called Weibel-Palade bodies (WPBs). WPB exocytosis is coordinated by a complex network of Rab GTPases, Rab-effectors and SNARE proteins. We have previously identified STXBP1 as the link between the Rab27A-Slp4-a ...
ORGANISM(S): Homo sapiens (Human) 
2018-07-04 | PXD006176 | Pride
Endothelial cells Proteomics Weibel-palade body Snare machinery Syntaxin-3 Von willebrand factor 
ProteomicsA plasma proteomic exploration in the thromboembolic field
Background: The elevated risk on and health burden of thromboembolic events necessitates development of blood-based patient risk monitoring.Objective: We explored the potential of mass spectrometry-based plasma proteomics to provide insights into underlying plasma protein signatures with treatment a...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD044173 | Pride
Proteomics Thromboembolism Anticoagulation Mass spectrometry 
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