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TranscriptomicsRNAseq of doxorubicin exposed SV40 immortalized human cardiomyocytes
The purpose of this experiment was to generate an additional RNAseq dataset of human cardiomyocytes exposed to doxorubicin for 24 hours. For robustness 7 biological replicas were generated per exposure group.
ORGANISM(S): Homo sapiens 
2025-12-14 | E-MTAB-16038 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human liver cancer cell line HepG2 treated with doxorubicin alone or in combination with valproic acid or suberoylanilide hydroxamic acid against untreated controls
RNA sequencing was performed to characterize transcriptomic changes in the human hepatocellular carcinoma cell line HepG2 following treatment with doxorubicin (DOX), either alone or in combination with the histone deacetylase inhibitors valproic acid (VPA) or suberoylanilide hydroxamic acid (SAHA), ...
ORGANISM(S): Homo sapiens 
2026-03-24 | E-MTAB-16713 | biostudies-arrayexpress
TranscriptomicsSingle-Cell Transcriptomics of Acetaminophen-Induced Responses in Human 2D and 3D Liver Microtissues
This study aimed to investigate how liver cell culture architecture influences acetaminophen (APAP)-induced transcriptional responses at single-cell resolution. We used human liver microtissues composed of primary human hepatocytes (PHHs), Kupffer cells (KCs), and hepatic sinusoidal endothelial cell...
ORGANISM(S): Homo sapiens 
2025-09-01 | E-MTAB-15516 | biostudies-arrayexpress
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