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TranscriptomicsDisruption of ADNP-KDM1A-GTF2I complex drives neural differentiation imbalance in Helsmoortel-Van der Aa syndrome [multi-omic]
Here, to characterize HVDAS in a developmental setting, we generated cortical brain organoids of 5 control and 5 HVDAS lines and profiled them by single-cell RNA- and ATAC-seq. Organoids were grown for 30 days using the protocol 10.1016/j.stem.2019.08.002. To reduce batch effects and costs, and maxi...
ORGANISM(S): Homo sapiens 
2026-01-27 | E-MTAB-16422 | biostudies-arrayexpress
UnknownElectrosclerotherapy for capillary malformations: study protocol for a randomised within-patient controlled pilot trial.
Not available
S-EPMC5695370 | biostudies-literature
TranscriptomicsTranscription profiling of human THP-1 cells in response to treatment with lipo-polysaccharide for 1 or 4 hours
Effect of LPS in a time dependent manner (1hr or 4hr treatment v untreated) on the THP-1 cell using a focused microarray containing 465 putative or known NF-kappaB regulated genes.
ORGANISM(S): Homo sapiens 
2006-09-29 | E-MEXP-868 | biostudies-arrayexpress
TranscriptomicsAbundant Quantitative Trait Loci for CpG Methylation and Expression Across Human Brain Tissues
A fundamental challenge in the post-genome era is to understand and annotate the consequences of genetic variation, particularly within the context of human tissues. We describe a set of integrated experiments designed to investigate the effects of common genetic variability on DNA methylation, mRNA...
ORGANISM(S): Homo sapiens 
2010-04-20 | E-GEOD-15745 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of asthma induced mice treated with LPS in a controlled environment
Examination of gene expression associated with asthma induced by treatment of mice with LPS in a controlled environment, realted experiment E-TIGR-7.
ORGANISM(S): Mus musculus 
2005-01-01 | E-TIGR-8 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of asthma induced mice treated with LPS in a controlled environment
Examination of gene expression associated with asthma induced by treatment of mice with LPS in a controlled environment. Related experiment E-TIGR-8
ORGANISM(S): Mus musculus 
2005-01-01 | E-TIGR-7 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of normal and malignant human breast epithelial cells
Multiple genome-wide microarrays have been used to analyse the transcriptomes of immunomagnetically separated normal human luminal epithelial and myoepithelial cells, as well as primary malignant breast epithelial cells.
ORGANISM(S): Homo sapiens 
2006-09-29 | E-TABM-66 | biostudies-arrayexpress
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