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TranscriptomicsGene expression microarray analysis of early oxygen-induced retinopathy (OIR)
Different inbred strains of rats differ in their susceptibility to OIR, an animal model of human retinopathy of prematurity. We examined gene expression profiles in Fischer 344 (F344, resistant to OIR) and Sprague Dawley (SD, susceptible to OIR) rats at the early time point of day 3 to identifying g...
ORGANISM(S): Rattus norvegicus 
2009-11-12 | E-GEOD-18998 | biostudies-arrayexpress
TranscriptomicsAIRE-deficient CD8+CD28low regulatory T lymphocytes fail to control experimental colitis
Mutations in the gene encoding the transcription factor AutoImmune REgulator (AIRE) are responsible for the ‘Autoimmune PolyEndocrinopathy Candidiasis Ecodermal Dystrophy’ syndrome. AIRE directs expression of tissue restricted antigens in the thymic medulla and in lymph node stromal cells and thereb...
ORGANISM(S): Mus musculus 
2011-06-22 | E-GEOD-30129 | biostudies-arrayexpress
TranscriptomicsMIcroRNA expression profiling of chemotherapy resistant esophageal adeno- and squamous cell carcinoma cell lines
Chemotherapy resistance adversely impacts the treatment of some individuals with esophageal cancer. Identifying chemotherapy resistance might help tailor clinical treatments. In this study the impact of microRNAs on chemotherapy resistance in esophageal cancer was investigated. We used microarrays t...
ORGANISM(S): Homo sapiens 
2013-08-28 | E-GEOD-50224 | biostudies-arrayexpress
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