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Cardiac profiling of miR expression levels in a transgenic mouse model of heart failure (MHC-CnA) to identify miRs that are co-regulated with the development of calcineurin-induced heart failure. Two-condition experiment: WT vs CnTg. Biological replicates: one array was performed on 3 pooled samples...
ORGANISM(S): Mus musculus 
In humans, cardiac hypertrophy is the principal risk factor for the development of overt heart failure and sudden cardiac death from lethal arrhythmias. Although aberrant reactivation of fetal² gene programs is intricately linked to maladaptive hypertrophy of postnatal cardiomyocytes, loss of cardi...
ORGANISM(S): Mus musculus 
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