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Atherosclerosis has an auto-immune component driven by self-reactive T and B cells. Identifying their antigenic drivers may lead to new diagnosis and treatment approaches. Here, we aim to identify immunogenic T cell epitopes derived from atherosclerosis-relevant proteins such as ApoB100 by studying ...
ORGANISM(S): Homo sapiens (Human) 
2025-09-18 | PXD068446 | Pride

Ferroptosis is a form of regulated cell death with roles in degenerative diseases and cancer. Excessive iron-catalyzed peroxidation of membrane phospholipids, especially those containing the polyunsaturated fatty acid arachidonic acid (AA), is central in driving ferroptosis. Here, we reveal that ...

2023-09-06 | MTBLS8280 | MetaboLights
Monoclonal antibodies (mAbs) can undergo post-translational modifications (PTMs) in the production process, these are part of the critical quality attributes (CQA) to ensure protein safety. Charge variants are important PTMs in mAbs and can be separated by using capillary zone electrophoresis (CZE)....
ORGANISM(S): Monoclonal Antibodies 
2024-04-12 | MSV000094521 | MassIVE
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