A timer gene network is spatially regulated by the terminal system in the Drosophila embryo
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ABSTRACT: We present an imaging dataset used to study the regulation of the "timer" genes caudal (cad), Dichaete (D) and odd-paired (opa) in early Drosophila melanogaster embryos (accompanying manuscript: doi.org/10.7554/eLife.78902). The dataset consists of various multiplexed HCR and/or antibody stains showing the expression of relevant patterning genes in fixed Drosophila embryos (54 gene product combinations across 12 genotypes). In total it contains 866 multi-chanel image stacks, 818 of which show whole embryos, and 48 of which show close-up views of the posterior terminal region. We used the data to identify 11 new regulatory interactions involved in Drosophila anteroposterior patterning and to clarify the dynamics and mechanism of posterior terminal patterning.
ORGANISM(S): Drosophila melanogaster (fruit fly)
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PROVIDER: S-BIAD582 | bioimages |
REPOSITORIES: bioimages
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