Dataset Information


Xu2002 - Blood Coagulation Model of Activated Factors with Platelet Activation

ABSTRACT: System of ODEs to describe the dynamics of several activated factors of blood coagulation. Publication introduces a platelet activation term for synthesis of Xa and IIa.

SUBMITTER: Matthew Roberts  

PROVIDER: MODEL1806130001 | BioModels | 2018-06-13


altmetric image


Dynamic model of the role of platelets in the blood coagulation system.

Xu C Q CQ   Zeng Yan Jun YJ   Gregersen Hans H  

Medical engineering & physics 20021101 9

In order to confirm which process is the most important in the blood coagulation cascade, a dynamic model of the function of platelets in blood coagulation is provided based on biochemical experiments. A series of conclusions based on qualitative analysis and mathematical simulation are drawn about the influence of the activation rate of factor VIII and factor IX on the generation of thrombin (IIa). It is evident that the pro-coagulation stimulus must exceed a threshold value to initiate the coa  ...[more]

Similar Datasets

2018-06-13 | MODEL1806130002 | BioModels
2019-07-10 | BIOMD0000000747 | BioModels
2018-07-18 | MODEL1807180003 | BioModels
2011-09-27 | GSE27917 | GEO
2011-09-26 | E-GEOD-27917 | ArrayExpress
| GSE99737 | GEO
2018-06-05 | MODEL1806050001 | BioModels
2014-07-17 | E-GEOD-59488 | ArrayExpress
| GSE96533 | GEO
2015-01-20 | E-GEOD-50858 | ArrayExpress