Comparisons of gene expressions in zebrafish (Danio rerio) brain and gill after cold acclimation

ABSTRACT: Ambient temperature affects organisms comprehensively, however cold responses are different among tissues. Here, we adopt a transcript screening approach to explore and compare the cold responses in zebrafish gills and brain. Zebrafish were exposed to cold and the oligonucleotide-based microarray was used to identify cold-induced genes. Principle component analysis (PCA) of the gene expression profiles indicated that gills develop different strategies for the increasing of exposure period while brain relatively remained stable. Combining statistic and clustering methods, we found that gills showed higher protein metabolism and cell activity while brain showed higher stress responses and detoxification during cold acclimation. According to the microarray data sets, we extended the study on

ORGANISM(S): Danio rerio

SUBMITTER: Ming Yi Chou 

PROVIDER: E-GEOD-10958 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress