Lactococcus lactis response to isoleucine starvation

ABSTRACT: Amino acid assimilation and metabolism are crucial for bacterial growth and survival and this is particularly obvious for lactic acid bacteria (LAB) that are generally auxotroph for various amino acids. However, amino acid assimilation is poorly characterized and a complete description of the response during amino acid starvation is still lacking in LAB. In this context, the global response of the LAB model Lactococcus lactis was characterized during isoleucine starvation in batch culture. The stress was imposed by isoleucine natural consumption in an initially rich chemically defined medium. Dynamic analyses were performed both using transcriptomic and proteomic approaches. The response was found to occur gradually and could be divided into three major parts that were firstly deduced from

ORGANISM(S): Lactococcus lactis

SUBMITTER: Muriel Cocaign-Bousquet 

PROVIDER: E-GEOD-12962 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress