Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Rat liver. Control vs. Chemical treated, 28 days


ABSTRACT: The final goal of this study is to develop a short term and highly accurate prediction method of carcinogenicity based on gene expression profile of rats administrated by carcinogens. We conducted 3 days-, 14 days- and 28 days-repeated dose experiments in male F344 rats with 47 carcinogens and 26 non-carcinogens, and the gene expression profiles in liver were investigated by custom glass microarrays. Supplementary file "73 Compounds for training" indicates 47 carcinogens and 26 non-carcinogens. Supplementary file "15 Compounds for test" lists the other compounds which are for test. Two-condition experiment, control vs. chemical treated rat liver. Biological replicates: 4 control, 4 treated, control samples were pooled. One replicate per array.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Hiroshi Matsumoto 

PROVIDER: E-GEOD-16394 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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