MOYO-S and MOYO-R responsive genes to dengue-2 infection at 3hr and 18hr post-infection times

ABSTRACT: We conducted a genome-wide survey of genes in Ae. aegypti females that are transcriptionally responsive upon challenge with dengue virus (serotype-2). The array was designed with 60-mer oligos specific to 16,092 gene transcripts of gene build AaegL1.1 (www. vectorbase.org). The hybridizations were performed at NimbleGen. We provided total RNA purified from the infected and control samples to NimbleGen. To identify dengue-specific transcription response (DTR) genes of MS and MR females upon infection with DENV2-JAM1409, a total of 15 independent samples (12 test samples and 3 control samples) were used for array hybridizations. These consisted of four DENV2 infected samples (MS-3hr, MR-3hr, MS-18hr and MR-18hr, post-infection, respectively) and a control sample that consisted of RNA isolate

ORGANISM(S): Aedes aegypti

SUBMITTER: David Severson 

PROVIDER: E-GEOD-16563 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress