Transcription profiling of human dermal pericytes compared to the remaining dermal cells of neonatal human foreskin

ABSTRACT: Pericytes derived from skin dermis can substantially enhance the short-term tissue-regenerative capacity of human epidermal cells already committed to differentiation; they also display both phenotypic and functional properties of mesenchymal stem cells. In this microarray analysis, we compared the gene expression profile of dermal pericytes to that of the remaining dermal cells of neonatal human foreskin. Experiment Overall Design: Human neonatal foreskin was digested overnight in dispase II at 4°C to separate the epidermis from the dermis. Subsequently the dermis was digested for 1-2 hours at 37°C in a mixed dispase and collagenase solution and then fractionated into two populations, i.e. pericytes (HD-1bri) and the remaining dermal cells (HD-1dim), on the basis of differential VLA-1 e

ORGANISM(S): Homo sapiens

SUBMITTER: Holger Schlueter 

PROVIDER: E-GEOD-17014 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress