Transcriptional response of Candida dubliniensis during hypha formation and environmental change

ABSTRACT: Transcriptional response of Candida dubliniensis during hypha formation and environmental change (temperature, pH, density and nutrients). Transcript profiling of C. dubliniensis identified a core shared transcriptional response with C. albicans during hypha formation and growth at alkaline pH. However, C. albicans expresses several unique hypha-specific genes, including ALS3, HYR1 and SAP4 and 5. Transcript profiling also revealed a novel role for NRG1 in regulating ferric reductases in C. dubliniensis. 8 experimental parameters were analysed, each carried out in quadruplicate. Dye-swaps were performed.

ORGANISM(S): Candida dubliniensis

SUBMITTER: Gary Moran 

PROVIDER: E-GEOD-20537 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress