Gene expression patterns in Schistosoma mansoni larvae and eggs

ABSTRACT: Protein variation in blood-dwelling schistosome worms generated by differential splicing of micro-exon gene transcripts. The infective schistosome cercaria develops from an undifferentiated germ ball within the daughter sporocyst in the molluscan host, during which considerable morphological development and synthesis of proteins essential for infection occurs. The free-living, non-feeding cercaria is notable for its swimming and host location behaviour. On contact with host skin it rapidly penetrates, replaces its tegument surface membranes, and begins body remodelling, before crossing the dermis to exit the skin via a blood vessel. Such a ‘violent’ transition from snail to fresh water to mammalian host should be accompanied by remarkable changes in the patterns of gene expression. All g

ORGANISM(S): Schistosoma mansoni

SUBMITTER: Ricardo DeMarco 

PROVIDER: E-GEOD-22037 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress