Gene expression analysis of relapse and no-relapse Wilms tumor

ABSTRACT: Wilms tumor (WT), the commonest renal tumor of the childhood, is originated from pluripotent metanephric blastemal cells resulting in tumors with triphasic histology, composed by blastemal, epithelial, and stromal cells. Histological subtype and tumor stage have long been recognized as important prognostic factors and used for the current therapeutic approach with blastema considered as the component with the highest clinical impact. Current clinical and molecular research is directed toward identifying prognostic factors for both purposes, definition of the minimal or intense required therapy for successful treatment of children with low or high risk of relapse, respectively. In this study, to identify molecular prognostic markers predictive of tumor relapse, samples from 26 advanced (Sta

ORGANISM(S): Homo sapiens

SUBMITTER: Mariana Maschietto 

PROVIDER: E-GEOD-22696 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress