Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Expression data of SW480 cells with TFAP2E overexpression and without TFAP2E (empty vector control)

ABSTRACT: AP2 transcription factors play important roles in development and cancer, we tried to clarify the role of the so far uncharacterised TFAP2E in colorectal cancer. We used GENE ST 1.0 Arrays to detail up and downregulated target genes of this AP-2 transcription factor. We used the ptarget mammalian expression vector (Promega) to overexpress the TFAP2E gene in the SW480 CRC line.

ORGANISM(S): Homo sapiens

SUBMITTER: Marc Taenzer 

PROVIDER: E-GEOD-23698 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Json Xml
altmetric image

Publications

<h4>Background</h4>Chemotherapy for advanced colorectal cancer leads to improved survival; however, predictors of response to systemic treatment are not available. Genomic and epigenetic alterations of the gene encoding transcription factor AP-2 epsilon (TFAP2E) are common in human cancers. The gene encoding dickkopf homolog 4 protein (DKK4) is a potential downstream target of TFAP2E and has been implicated in chemotherapy resistance. We aimed to further evaluate the role of TFAP2E and DKK4 as p  ...[more]

Similar Datasets

Transcriptomics Expression data of SW480 cells with TFAP2E overexpression and without TFAP2E (empty vector control)
2013-08-09 | GSE23698 | GEO
Transcriptomics Expression analysis of colorectal cancer cell line SW480 expressing FOXC2
2014-07-02 | E-GEOD-58980 | biostudies-arrayexpress
Transcriptomics MicroRNA expression profile between human colorectal cancer SW480 and SW620 cell line
2016-08-01 | E-GEOD-72412 | biostudies-arrayexpress
Transcriptomics Wnt signaling pathway gene expression profile in SW480 cells with/without hiNOS overexpression
2013-08-20 | E-GEOD-50009 | biostudies-arrayexpress
Transcriptomics Expression data from SW480 cells with Gankyrin knockdown
2013-02-04 | E-GEOD-44029 | biostudies-arrayexpress
Transcriptomics Human SW480 cells: Untreated vs H2O2 Treated
2011-12-01 | E-GEOD-32382 | biostudies-arrayexpress
Proteomics SW480 N-terminal peptide analysis
2023-07-20 | PXD039053 | Pride
Transcriptomics SW480 Signaling Hub Inhibition
2011-06-03 | E-GEOD-29689 | biostudies-arrayexpress
Proteomics TET2 binding protein of human colon cancer cell SW480-SW620
2023-10-24 | PXD020080 | Pride
Transcriptomics mRNA-seq of SW480 USP22 knockdown cells
2019-12-05 | E-MTAB-8214 | biostudies-arrayexpress