Extraction of Total RNA from Single Neurons: Mauthner-cell Cytoplasm vs. Whole Brain

ABSTRACT: Astatotilapia burtoni males change their startle behavior in accordance with changes in a socially-mediated phenotypic state. When dominant (DOM), males are brightly colored, isolated from the school and startle readily in response to an auditory pulse. When subordinate (SUB), males are cryptically colored, school and startle less frequently. We hypothesize that the difference in startle responsiveness is governed by serotonergic modulation on the command-like Mauthner cells (M-cells). We used the selective serotonin receptor subtype 2 (5HTR2) antagonist ketanserin to show that serotonin receptors can modulate startle frequency and that the behavioral difference correlates with differences in electrophysiological recordings of M-cells. Specifically, SUB males have a higher serotonergic ton

ORGANISM(S): Haplochromis burtoni

SUBMITTER: Lin Huffman 

PROVIDER: E-GEOD-26277 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress