Msx1 ChIP-Seq from C2C12 murine myoblast cells expressing Flag-Msx1 protein

ABSTRACT: The spatial and temporal control of gene expression during development requires the concerted actions of sequence-specific transcriptional regulators and epigenetic chromatin modifiers, which are thought to function within precise nuclear compartments. However, how these activities are coordinated within the dynamic context of the nuclear environment is still largely unresolved. Here we show that transcriptional repression by the Msx1 homeoprotein coordinates recruitment of Polycomb to genomic targets with localization to the nuclear periphery. We used genome-wide ChIP-Seq analyses to identify genomic binding sites for Msx1 in C2C12 murine myoblast cells. C2C12 myoblast cells were seeded at a density of 2.5 x 10^5 cells / 10-cm plate one day prior to infection, and infected with a retrovir

ORGANISM(S): Mus musculus

SUBMITTER: Richard Young 

PROVIDER: E-GEOD-26711 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress