Inhibition of Bcl6-SMRT/NCoR interactions by an inhibitory peptide affects inflammatory pathways

ABSTRACT: Using microarrays, we compared the changes in levels of gene expression between wild type mouse bone marrow derived macrophages upon treatment with the Bcl6 peptide inhibitor, RI-BPI, that specifically blocks interaction between BCL6 and the co-repressors NCoR or SMRT. Total RNA was obtained from cultered wild type primary bone marrow-derived macrophages that were treated with either 5 μM control or RI-BPI peptide in MSF media for 12 hours.

ORGANISM(S): Mus musculus

SUBMITTER: Ruth Yu 

PROVIDER: E-GEOD-27001 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress