Gene expression profiles in kidney of Japanese flounder injected with formalin-killed bacterial cells

ABSTRACT: In order to identify the genes induced by different bacterial cells, which may contain different types of pathogen associated molecular patterns (PAMPs), high-throughput gene expression analyses using Agilent custom-oligo DNA microarray containingon 9,573 probes constructed for Japanese flounder Paralichthys olivaceus were conducted. A number of genes showed significant changes in mRNA levels. However, there are no significant difference in a manner of the changes among the different bacterial cell treatments. The genes significantly induced by the treatments included well-known immune-related genes such as granulocyte-colony stimulation factor, haptoglobin, hepcidin. The kidney were isolated from the formalin killed cells (FKCs) intraperitoneal injected Japanese flounder, Paralichthys

ORGANISM(S): Paralichthys olivaceus

SUBMITTER: Hidehiro Kondo 

PROVIDER: E-GEOD-29219 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress