L. plantarum growth curve experiment sampled a different optical densities

ABSTRACT: Specific Lactobacillus strains are marketed as probiotics i.e. health promoting organisms. As previously shown in vivo, L. plantarum WCFS1 modulates immune responses via nuclear factor (NF)kB in a growth phase dependent manner, likely caused by changed microbial cell surface characteristics. Here, we identified the differential cell-surface proteome composition of L. plantarum WCFS1 cells derived from the mid-logarithmic and late stationary growth phase by surface trypsination of intact bacterial cells, followed by a combined 1D- and 2D-LC-MS shotgun proteomics strategy, and growth phase dependent transcriptome analysis. Overall, these analyses led to the identification of 31 surface proteins differentially present in the logarithmic and stationary phase, whereas additional 17 and 33 prote

ORGANISM(S): Lactobacillus plantarum WCFS1

SUBMITTER: Michiel Wels 

PROVIDER: E-GEOD-31000 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress