Salmonella Enteritidis strains from poultry show differential responses to stress and survival in the egg albumen

ABSTRACT: Salmonella Enteritidis is the major food-borne pathogen primarily causing human infection through contaminated chicken meat and eggs. We recently demonstrated that S. Enteritidis strains from poultry differ in their ability to invade human intestinal cells and cause disease in orally challenged mice. Here we hypothesized that the differential pathogenicity of S. Enteritidis strains is due to the differential fitness in the adverse environments that may be encountered during infection in the host. The response of a panel of six S. Enteritidis strains to acid stress, oxidative stress, survival in egg albumen and the ability to cause infection in chickens were analyzed. This analysis allowed classification of strains into two categories: stress- sensitive and stress- resistant, with the forme

ORGANISM(S): Salmonella enterica subsp. enterica serovar Enteritidis

SUBMITTER: Devendra Shah 

PROVIDER: E-GEOD-33102 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress