Dual inactivation of Akt and ERK by small molecule TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction and potent anti-tumor effects

ABSTRACT: TIC10-induced transcriptional changes at 48hrs in HCT116 p53-null cells (10uM). Six samples of HCT116 p53-null cells with TIC10 (10uM) or DMSO treatment. Three replicates each.

ORGANISM(S): Homo sapiens

SUBMITTER: Joshua Allen 

PROVIDER: E-GEOD-34194 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress