Genomic signatures of a global fitness index in a multi-ethnic cohort of women

ABSTRACT: The rates of obesity and sedentary lifestyle are on a dramatic incline, with associated detrimental health effects among women in particular. Although exercise prescriptions are useful for overcoming these problems, success can be hampered by differential responsiveness among individuals in cardiovascular fitness indices (i.e., improvements in strength, lipids, VO2max). Genetic factors appear to play an important role in determining this inter-individual variation in responsiveness. We performed microarray analyses on mRNA in whole blood from 60 sedentary women from a multi-ethnic cohort who underwent 12 weeks of exercise, to identify gene subsets that were differentially expressed between individuals who experienced the greatest and least improvements in fitness based upon a composite fi

ORGANISM(S): Homo sapiens

SUBMITTER: Evadnie Rampersaud 

PROVIDER: E-GEOD-34788 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress