Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Expression data of differentiated human erythroid cells with or without Tranylcypromine (TC) treatment


ABSTRACT: We found that LSD1 inhibition by a monoamine oxidase inhibitor, tranylcypromine (TC), could enhance fetal gamma globin expression. Global effects of TC on erythroid expession were conducted by HG-U219 array strips. Primary human erythroid cells, which differentiated from CD34+ cells for 8 days, were harvested before or and after TC treatment (0.5 µM, 1.5 µM or 5 µM) for the gene expression analysis.

ORGANISM(S): Homo sapiens

SUBMITTER: Lihong shi 

PROVIDER: E-GEOD-42078 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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