Chronic alcohol consumption from adolescence-to-adulthood in mice M-bM-^@M-^T Effect on gene expression in the hypothalamus

ABSTRACT: We employed a paradigm of chronic moderate alcohol intake from adolescence-to-adulthood in mice, and analyzed the alcohol effect on both behavioral and hypothalamic gene expression changes. We employed a paradigm of chronic moderate alcohol intake from adolescence-to-adulthood in mice. Before chronic alcohol drinking began, mice (3 weeks old) were allowed to adapt to drinking tubes with both tubes containing water from experimental day 1-5. After adaptation period, mice were randomly aside to 5% alcohol group, 10% alcohol group or water-only control group (n=16-18). Chronic alcohol drinking lasted to day 57 of the experiment without any change and interruption. Then each mouse is sacrificed by decapitation, and the hypothalamus was dissected for rapid freeze and storage at -80 M-BM-:C. Hyp

ORGANISM(S): Mus musculus

SUBMITTER: ke wang 

PROVIDER: E-GEOD-42770 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress