Unknown,Transcriptomics,Genomics,Proteomics

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Identification of inflammation-related microRNAs deregulated in the plasma from intracerebral hemorrhage patients

ABSTRACT: We tested the hypothesis that circulating microRNAs (miRNAs) present in plasma might display a specific signature in patients with intracerebral hemorrhage (ICH). Global miRNA profiles were determined with the Agilent Human miRNA Microarray platform, 027233. ICH patients display a characteristic inflammation-related miRNA profile as compared to healthy controls. Plasma samples were collected from the following 6 subject groups: male ICH patients (n=8), female ICH patients (n=7), male healthy control (n=4), female healthy control (n=4), male ischemic stroke patients (n=8) and female ischemic stroke patients (n=8). Total RNAs isolated from 1 ml plasma were pooled for each group. A fixed volume of RNA sample was withdrawn from each pool and used for microarray detection.

ORGANISM(S): Homo sapiens

SUBMITTER: Fan Jiang

PROVIDER: E-GEOD-43618 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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