A novel aCGH method for non-model organisms for assessing genomes and de-novo transcriptome sequencing reads (Staphylococcus aureus)

ABSTRACT: Genomes and transcriptomes of non-model organisms can be analyzed using next-generation sequencing technologies, but de-novo sequencing and annotating a full eukaryotic genome is still challenging. So, -omics experimentation with non-model organisms requires a suite of technologies to obtain reliable results in a cost-effective manner. Here, a novel method for microarray-based genome analysis is presented which is especially suitable for non-model organisms. We show that it is useful for complementing regular aCGH analyses and for evaluating transcriptome next-generation sequencing reads. The principle of the method is straightforward: feature intensities obtained after hybridizing the test genome are compared with the feature intensities of a control hybridization. The control hybridizati

ORGANISM(S): Staphylococcus aureus

SUBMITTER: Paul Wackers 

PROVIDER: E-GEOD-51148 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress