Activin A and BMP4 Modulation of Wnt/?-catenin Signaling Directs Fate Specification of Mesoderm Derivatives from Human Embryonic Stem Cells

ABSTRACT: We report the derivation of 2 different methods of generating cardiac myocytes from human ESCs. The traditional route is via cardiac progenitor cells and the second, new approach is through re-directing hemogenic endothelium into the cardiac lineage using inhibition of Wnt/b-catenin signaling Examination of 2 different cardiac populations using RNA-seq

ORGANISM(S): Homo sapiens

SUBMITTER: Chuck Murry 

PROVIDER: E-GEOD-55275 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress