GPBAR1 agonism has a broad impact on blocking macrophage activation

ABSTRACT: Human D14+ / CD16+ monocytes were treated with GPBAR1 agonists or controls, and were stimulated with interferon gamma and LPS. At 6 and 24 hours, the cells were profiled by RNAseq 40 total samples, 5 per group with eight groups. Individual donors used for multiple comparisons, so paired analysis is possible. Control samples include unstimulated cells, and stimulated cells treated with vehicle control (DMSO).

ORGANISM(S): Homo sapiens

SUBMITTER: Jonathan Hill 

PROVIDER: E-GEOD-57494 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress