Genome-wide transcriptome analysis revealed extensive alternative RNA splicing in gene expression in the zoonotic parasite Schistosoma japonicum

ABSTRACT: Background: Schistosoma japonicum is a pathogen of the phylum Platyhelminths that causes zoonotic schistosomiasis endemic in China and Southeast Asian countries. Control of the disease has been hampered by the lack of efficient measures. The development of tools for diagnosis of acute and chronic infection, and novel antiparasite reagents all relies on the understanding of the biological mechanism of the parasite. Results: In this study, the polyadenylated transcripts from the male and female S. japonicum were sequenced by a high-through-put RNA-seq technique. Bioinformatic and experimental analyses were focused on the posttranscriptional RNA processing, which at the first time revealed the extensive alternative splicing events occurred in the adult stage of the parasite. The number of

ORGANISM(S): Schistosoma japonicum

SUBMITTER: Xianyu Piao 

PROVIDER: E-GEOD-58564 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress