BATSeq of ESC-FCS/ESC-2i/NSC
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Lars Velten
PROVIDER: E-GEOD-60768 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Single-cell polyadenylation site mapping reveals 3' isoform choice variability.
Velten Lars L Anders Simon S Pekowska Aleksandra A Järvelin Aino I AI Huber Wolfgang W Pelechano Vicent V Steinmetz Lars M LM
Molecular systems biology 20150603 6
Cell-to-cell variability in gene expression is important for many processes in biology, including embryonic development and stem cell homeostasis. While heterogeneity of gene expression levels has been extensively studied, less attention has been paid to mRNA polyadenylation isoform choice. 3' untranslated regions regulate mRNA fate, and their choice is tightly controlled during development, but how 3' isoform usage varies within genetically and developmentally homogeneous cell populations has n ...[more]
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