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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptom analysis of FLT1 regulated genes in metastasis associated macrophages

ABSTRACT: Gene expression changes in metastasis associated macrophage (MAM) with control and FLT1 inhibitory antibody (MF1) were compared using FACS sorted cells from mice bearing pulmonary metastasis of breast tumor cells treated with Ctrl and MF1 antibody A six chip study using total RNA recovered from metastasis associated macrophages from three separate mice treated with FLT1 inhibitory antibody (MF1) and three separate mice treated with control antibody. Each chip measures the expression level of 42586 genes.

ORGANISM(S): Mus musculus

SUBMITTER: Bin-Zhi Qian

PROVIDER: E-GEOD-68843 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcriptom analysis of differentially regulated genes in metastasis associated macrophages(MAM) compared with lung and spleen resident macrophages

Project description:Gene expression changes in metastasis associated macrophage (MAM) FACS sorted cells from mice bearing pulmonary metastasis of breast tumor cells were compared with lung and spleen resident macrophages sorted from healthy mice using same sorting protocol. A six chip study using total RNA recovered from metastasis associated macrophages from three individual mice and lungs and spleens all from three individual mice. Each chip measures the expression level of 42586 genes.

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