Transcriptome analysis of sexual dimorphism in the somatic gonadal precursor cells of Caenorhabditis elegans

ABSTRACT: The Caenorhabditis elegans somatic gonad was the first organ to have its cell lineage determined, and the gonadal lineages of the two sexes differ greatly in their pattern of cell divisions, cell migration and cell types. Despite much study, the genetic pathways that direct early gonadal development and establish its sexual dimorphism remain largely unknown, with just a handful of regulatory genes identified from genetic screens. To help define the genetic networks that regulate gonadal development, we employed cell-specific RNA-seq. We identified transcripts present in Z1/Z4 or Z1/Z4 daughter cells in each sex at the onset of somatic gonadal sexual differentiation. For comparison, transcripts were identified in whole animals at both time points. Pairwise comparisons of samples identified

ORGANISM(S): Caenorhabditis elegans

SUBMITTER: Mary Kroetz 

PROVIDER: E-GEOD-71772 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress