Cell cycle dependent nucleosome occupancy at cohesin binding sites in yeast chromosomes
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Zhifeng Shao
PROVIDER: E-GEOD-8130 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Cell cycle-dependent nucleosome occupancy at cohesin binding sites in yeast chromosomes.
Liu Jie J Czajkowsky Daniel M DM Liang Shoudan S Shao Zhifeng Z
Genomics 20080301 3
In the budding yeast, cohesin is loaded onto the chromosome during the late G1 phase, establishes sister chromatid cohesion concomitant with DNA replication, and dissociates by the telophase. Here, using oligonucleotide tiling arrays, we show that, at the anaphase, nearly all of the cohesin binding sites contain nucleosome-free regions. The majority of these sites remain nucleosome-free throughout the cell cycle, consistent with the suggestion of a DNA-binding anchoring protein present at these ...[more]
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