Regulation of gene expression in Streptococcus gordonii by coaggregation with Actinomyces naeslundii

ABSTRACT: Oral streptococci, including Streptococcus gordonii, and Actinomyces naeslundii, are consistently found to be the most abundant bacteria in the early stages of dental plaque accumulation. These organisms interact physically (coaggregate) in vitro and in vivo. We hypothesized that coaggregation between S. gordonii and A. naeslundii leads to changes in gene expression in the partner organisms. Furthermore, we predicted that coaggregation-induced changes in phenotype contribute to the success of streptococci and actinomyces in dental plaque. To assess the responses of S. gordonii to coaggregation with A. naeslundii, RNA was extracted from S. gordonii cells 3 h after inducing coaggregation with A. naeslundii or from equivalent S. gordonii monocultures. The two RNA populations were reverse tran

ORGANISM(S): Streptococcus gordonii str. Challis

SUBMITTER: Nicholas Jakubovics 

PROVIDER: E-GEOD-9478 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress