Transcription profiling of Strongyloides ratti parasitic females experiencing an anti-S. ratti low or high imumne response measured at 15 or 6 days of infection

ABSTRACT: We wished to determine the changes in gene expression that occurred in S. ratti parasitic females as an infection progressed and thus as these stages are exposed to an anti-S. ratti immune response. To do this we compared gene expression in parasitic females recovered 6 days p.i. (i.e. no or very low immune response) with those recovered at 15 days p.i. (i.e. high immune response); for convenience, we refer to these as parasitic females subject to "low immune pressure" and "high immune pressure", respectively. These days were chosen because previous analyses of S. ratti parasitic females have shown significant differences in the size, appearance etc. of worms at these time points. The experimental design used, was to have at least three biological replicates for each sample (i.e. three ind

INSTRUMENT(S): Axon- GenePix4000B

ORGANISM(S): Strongyloides ratti

DISEASE(S): hign immune pressure

SUBMITTER: Fiona Thompson 

PROVIDER: E-MEXP-1010 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress