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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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RNA-Seq of the liver and muscle of chickens differing in feed conversion efficiency (FCE)

ABSTRACT: Chickens (Cobb500FF) divergent in residual feed intake were analyzed for the muscle and liver transcriptomic profiles.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Gallus gallus

SUBMITTER: Nares Trakooljul

PROVIDER: E-MTAB-12147 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcriptional shifts account for divergent resource allocation in feed efficient broiler chickens

Project description:Chickens (Cobb500FF) divergent in residual feed intake were analyzed for muscular (M. pectoralis), duodenal, jejunal and ileal transcriptomic profiles.

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RNA-seq of muscle from pigs divergent in feed efficiency and product quality

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RNA-seq of liver from pigs divergent in feed efficiency highlights shifts in macronutrients metabolism, hepatic growth and immune response

Project description:Liver is a metabolically complex organ that influences nutrient partitioning and potentially modulates the efficiency of converting energy acquired from macronutrients ingestion into a muscle and/or adipose tissue (referred to as feed efficiency, FE). The objective of this study was to sequence the hepatic tissue transcriptome of pigs divergent for FE and identify relevant biological processes that underpin the differences in liver phenotypes and FE.

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RNA-seq of adipose tissue from pigs divergent in feed efficiency reveals variations in adipose growth, extracellular matrix formation, lipid metabolism and immune response

Project description:Feed efficiency (FE) is an indicator of efficiency in converting energy, attained from macronutrient ingestion, into tissue. Adipose tissue, besides being a master regulator of systemic lipid storage, is also an active endocrine organ that communicates with skeletal muscle, liver and brain to influence appetite, lipid & glucose metabolism and energy homeostasis. Adipose tissue is hypothesised to play a vital part in regulation of FE. The objective of the present study was to sequence the subcutaneous adipose tissue transcriptome in FE-divergent pigs (n=16) and identify relevant biological processes underpinning observed differences in FE.

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Identification of differential duodenal gene expression levels correlated with differences in energy utilization in chickens

Project description:The amount of energy that can be extracted from a diet varies between individuals. Apparent Metabolizable Energy (AME) is a measure of energy utilization efficiency and represents the difference between the energy consumed and the energy lost via the excreta. There are significant differences in the energy utilization capability of individual birds that have a similar genetic background and are raised under identical conditions. We analyzed duodenal gene expression and microbiota differences between birds with different efficiencies in food to energy conversion using microarrays and sequencing of 16s rRNA genes. Differences were found in duodenal gene expression between high and low AME birds, they were however mostly related to genes of unknown function. The flock of 96 chickens was used to study ability of the bird to utilise the energy from feed. We measured energy content in feed and in excreta of individually housed birds. The microarrays were used to compare expression between the best and worst energy utilisers.

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Transcriptome analysis of mRNA expression in skeletal muscle of Yorkshire pigs with differential residual feed intake

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A comparative analysis of the transcriptome profiles of liver and muscle tissue in pigs divergent for feed efficiency

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Transcription profiling of chicken adipose tissue at 7-week of age

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