Mitochondrial Pyruvate Carrier Inhibition Activates the Integrated Stress Response in Human Hair Follicles - RNAseq

ABSTRACT: UK-5099 is a pharmacological inhibitor of MPC1, a protein that transports pyruvate into mitochondria. Human hair follicles were treated with vehicle, and 10 µM and 40 µM UK-5099 for 48h ex vivo. RNASeq was performed to determine whether MPC1 inhibition induces transcriptional changes in the hair follicle.

INSTRUMENT(S): Illumina HiSeq 4000

ORGANISM(S): Homo sapiens

SUBMITTER:  

PROVIDER: E-MTAB-13350 | biostudies-arrayexpress |

SECONDARY ACCESSION(S): ERP151207

REPOSITORIES: biostudies-arrayexpress