Mitochondrial Pyruvate Carrier Inhibition Activates the Integrated Stress Response in Human Hair Follicles - RNAseq
Ontology highlight
ABSTRACT: UK-5099 is a pharmacological inhibitor of MPC1, a protein that transports pyruvate into mitochondria. Human hair follicles were treated with vehicle, and 10 µM and 40 µM UK-5099 for 48h ex vivo. RNASeq was performed to determine whether MPC1 inhibition induces transcriptional changes in the hair follicle.
INSTRUMENT(S): Illumina HiSeq 4000
ORGANISM(S): Homo sapiens
SUBMITTER:
PROVIDER: E-MTAB-13350 | biostudies-arrayexpress |
SECONDARY ACCESSION(S): ERP151207
REPOSITORIES: biostudies-arrayexpress
ACCESS DATA