Comparison of the methylation profiles of children with developmental language disorder and healthy control subjects

ABSTRACT: Developmental language disorder (DLD), previously known as specific language impairment, is a neurodevelopmental disorder. It affects approximately 7% of school-age children. The affected children fail to develop normal speech and language skills. This is a major public health concern as it adversely impacts the communication, academic, and social skills of the affected individual. The human brain development is a complex process that involves the accurate orchestration of the expression of multiple genes. Precise temporal and spatial regulation of gene expression is essential for proper brain development. Epigenetic factors such as DNA methylation can modulate gene expression without altering the DNA sequence. They are, therefore, considered as key regulators of the expression of genes i

ORGANISM(S): Homo sapiens

SUBMITTER: Ayyappan Anitha 

PROVIDER: E-MTAB-13583 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress