Supporting datasets for: Mutation-resolved single-cell transcriptomics reveals enhanced β-amyloid clearance in TET2-mutant human monocytes
Ontology highlight
ABSTRACT: This study contains bulk RNA sequencing datasets generated from THP1-derived macrophages and primary monocyte-derived macrophages under M0 and M1 polarization conditions. Wild-type and TET2-deficient cells were analyzed to characterize transcriptional programs associated with TET2 loss-of-function and phagocytosis-related pathways.
INSTRUMENT(S): NextSeq 500
ORGANISM(S): Homo sapiens
SUBMITTER: xiao yang
PROVIDER: E-MTAB-17157 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
ACCESS DATA